Multiple Sclerosis
- Preventative strategies
- Development of biomarkers to determine who amongst first degree relatives of MS sufferers is at risk of development of disease
- Impact of Vitamin D supplementation
- Environmental factors involved in transformation to disease in susceptible patients
- New diagnostic and therapeutic targets
- The ANZgene consortium has identified and validated several novel loci that confer susceptibility to MS. Further mapping and functional studies are underway.
- Proteomics based study to identify molecules expressed in MS lesions to identify novel targets expressed by neural cell
- Diagnostic and therapeutic development
- Control of proliferation and differentiation of neural stem cells in models of disease
- Targeting novel cell surface receptors through antibody therapy