Multiple Sclerosis

  • Preventative strategies
    • Development of biomarkers to determine who amongst first degree relatives of MS sufferers is at risk of development of disease
    • Impact of Vitamin D supplementation
    • Environmental factors involved in transformation to disease in susceptible patients
  • New diagnostic and therapeutic targets
    • The ANZgene consortium has identified and validated several novel loci that confer susceptibility to MS. Further mapping and functional studies are underway.
    • Proteomics based study to identify molecules expressed in MS lesions to identify novel targets expressed by neural cell
  • Diagnostic and therapeutic development
    • Control of proliferation and differentiation of neural stem cells in models of disease
    • Targeting novel cell surface receptors through antibody therapy